Zesty Cajun Garlic Chicken

Featured in: Easy Weeknight Meals

This vibrant dish combines tender chicken pieces sautéed with Cajun seasoning and smoked paprika to create a spicy base. Soft cheese tortellini is cooked and then enveloped in a smooth, creamy Parmesan sauce enriched with garlic, butter, and heavy cream. Sweet bell peppers and onions add freshness and balance, while a garnish of chopped parsley offers a bright finish. Perfect for quick, comforting meals with a flavorful twist.

Updated on Thu, 13 Nov 2025 08:26:00 GMT
Zesty Cajun Garlic Parmesan Chicken Tortellini, a creamy pasta dish with tender chicken and spicy sauce. Save
Zesty Cajun Garlic Parmesan Chicken Tortellini, a creamy pasta dish with tender chicken and spicy sauce. | ovenharmony.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick.

I first made this dish when my family wanted something comforting and just a little spicy after a long day. The mix of cheesy tortellini with Cajun chicken quickly became a weeknight favorite in our home.

Ingredients

  • Chicken breasts: 2 large boneless, skinless, cut into bite-sized pieces
  • Cheese tortellini: 500 g (18 oz) refrigerated
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g) freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons chopped, for garnish
  • Optional: extra grated Parmesan for serving

Instructions

Cook the tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Sauté the chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 to 7 minutes. Remove chicken from skillet and set aside.
Sauté the vegetables:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3 to 4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Prepare the sauce:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add cheese and combine:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Return chicken and pasta:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Finish and serve:
Cook for an additional 2 to 3 minutes until heated through. Serve garnished with fresh parsley and extra Parmesan if desired.
Save
| ovenharmony.com

This dish reminds me of cozy dinners around our kitchen table during chilly evenings, laughter echoing as everyone reached for second helpings.

Required Tools

Large pot, large skillet, chefs knife, cutting board, wooden spoon or spatula, measuring cups and spoons

Allergen Information

Contains: Wheat (tortellini), Milk (cream, Parmesan, butter), Eggs (tortellini may contain eggs). Double-check tortellini packaging for specific allergens.

Nutritional Information (per serving)

Calories: 620, Total Fat: 29 g, Carbohydrates: 53 g, Protein: 38 g

Golden brown chicken and cheesy tortellini smothered in the flavorful Zesty Cajun Garlic Parmesan sauce. Save
Golden brown chicken and cheesy tortellini smothered in the flavorful Zesty Cajun Garlic Parmesan sauce. | ovenharmony.com

Enjoy this bold and creamy dish as a quick solution for any weeknight craving. Leftovers reheat beautifully the next day with an extra splash of cream.

Recipe FAQ

How do I achieve the best texture for the chicken?

Cut chicken into bite-sized pieces and sauté over medium-high heat until golden and cooked through, ensuring it remains tender and juicy.

Can I use fresh pasta instead of refrigerated tortellini?

Yes, fresh tortellini works well and cooks quickly; just adjust boiling time according to package or fresh preparation guidelines.

What substitutes can I use for Parmesan cheese?

Grana Padano or Asiago cheeses provide similar nutty flavors and melt smoothly in the sauce.

How can I make this dish spicier?

Add cayenne pepper or red pepper flakes along with the Cajun seasoning for an extra spicy kick.

Is there a way to lighten the sauce?

Substitute heavy cream with half-and-half or a mixture of milk and cream cheese for a lighter but still creamy sauce.

Zesty Cajun Garlic Chicken

Tender chicken and cheesy tortellini in a creamy, spicy garlic Parmesan sauce with fresh herbs.

Prep duration
15 min
Cook duration
25 min
Complete duration
40 min
Created by Claire Johnson

Classification Easy Weeknight Meals

Complexity Easy

Heritage American/Italian Fusion

Output 4 Portions

Dietary considerations None specified

Components

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 ounces refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 ½ cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 ½ teaspoon smoked paprika
03 ½ teaspoon black pepper
04 ½ teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley (for garnish)
03 Optional: extra grated Parmesan for serving

Directions

Phase 01

Cook tortellini: Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.

Phase 02

Sauté chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5-7 minutes. Remove chicken from skillet and set aside.

Phase 03

Cook vegetables: Add remaining olive oil and butter to the skillet. Sauté onion and bell pepper for 3-4 minutes until softened. Add garlic and cook for 30 seconds until fragrant.

Phase 04

Prepare sauce: Sprinkle remaining Cajun seasoning and smoked paprika into the skillet. Stir to combine, then pour in heavy cream. Bring to a gentle simmer, stirring frequently.

Phase 05

Incorporate cheese: Add Parmesan cheese and stir until melted and the sauce is smooth. Taste and adjust seasoning if necessary.

Phase 06

Combine chicken and tortellini: Return chicken to the skillet along with cooked tortellini. Toss gently to coat evenly with the sauce.

Phase 07

Finish cooking: Cook for another 2-3 minutes until heated through.

Phase 08

Serve: Garnish with fresh parsley and extra Parmesan if desired before serving.

Necessary tools

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy details

Review each component for potential allergens and consult healthcare professionals if you're unsure about ingredients.
  • Contains wheat (tortellini), milk (cream, Parmesan, butter), and eggs (tortellini may contain eggs). Verify packaging for specific allergens.

Nutritional information (each portion)

These values are approximate guidelines only and shouldn't replace professional medical guidance.
  • Energy: 620
  • Fats: 29 g
  • Carbohydrates: 53 g
  • Proteins: 38 g